A postdoctoral position in musculoskeletal magnetic resonance is available, shared between the Longitudinal Studies Branch (Luigi Ferrucci, Chief) and the Magnetic Resonance Imaging and Spectroscopy Section (Richard Spencer, Chief) at the National Institute on Aging (NIA) of the National Institutes of Health, located in Baltimore, Maryland. The work will center on spectroscopic and imaging studies of muscle in human subjects. Investigation of muscle lipids using proton spectroscopy and muscle bioenergetics using phosphorus spectroscopy are of particular interest. Results will be correlated with a wide range of other biological and functional outcomes to explore the basis and consequences of metabolic and energetic changes that occur with age and with age-associated disease. Other research opportunities may be available depending upon the interests and background of the successful candidate.
The research associated with this position will be performed primarily using our 3T whole-body Philips Achieva MRI system, capable of both proton and heteronuclear spectroscopy. Other MRI instrumentation at the NIA consists of a triple-resonance vertical wide-bore 9.4T Bruker Avance III spectrometer with microimaging and solids capability and a double-resonance Bruker 7T/30 cm Biospec Avance system for preclinical studies.
A background in MR imaging or NMR spectroscopy of muscle or connective tissue is preferred, although applications are also invited from individuals with experience in other areas of biological MRI and NMR. A strong background in MRI or NMR is required. The appointment will be as an IRTA Postdoctoral Fellow for US citizens or as a Visiting Fellow for non-citizens. Accordingly, applicants must have fewer than five years of postdoctoral experience.
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