Postdoctoral Fellow : Singapore, Singapore

CSI Singapore, National University of Singapore, is a state-of-the-art research center with a multifaceted and coordinated approach to cancer research, extending from basic cancer studies all the way to experimental therapeutics. The focus of the institute is on cancers endemic to Asian populations such as gastric, liver, lung, leukemia and breast cancers. The institute houses a full spectrum of research and clinical translational facilities. This major center is led by a team of world-class scientists with significant government funding from Singapore’s National Research Foundation and Ministry of Education.

We are seeking individuals with exceptional scientific credentials to join a vibrant, dynamic team at CSISingapore.

A postdoctoral position is available immediately in Dr Yvonne Tay’s lab for a highly motivated Ph.D. or M.D graduate with a background in molecular or cellular biology, biochemistry or other related fields who is interested in deciphering regulatory RNA networks in the context of cancer (reviewed in Tay et al, Nature 2014; also see Tay et al, Nature 2008 and Tay et al, Cell 2011). The successful candidate will design and conduct experiments, analyse data, write papers and grants, mentor students, and compete for fellowships.

Qualifications:
• A Ph.D. in cancer biology or related area
• Experience with in vivo animal models, particularly mice and/or zebrafish
• Expertise in RNA biology (including but not limited to microRNAs) is preferred
• Strong background and working knowledge of basic molecular and cellular biology techniques such as cell culture, cloning, real-time PCR and western blotting
• Experience with analyses of human clinical samples, RNA sequencing, RNA immunoprecipitation, mass spectrometry and/or CRISPR genome editing is highly desirable
• Ability to independently lead research projects and critically analyse data
• A proven track record in the form of publications in top international English language journals
• Ability to communicate in written and spoken English 
Applications should include full curriculum vitae, publication list, and names and contact information of 3 referees. Please also include a summary of your research experience.
*
*Related publications:
• Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. (2008) MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 455(7216),1124-1128.
o Selected by Faculty of 1000
• Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U, Karreth F, Poliseno L, Provero P, Di Cunto F, Lieberman J, Rigoutsos I, Pandolfi PP. (2011) Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 147, 344–357.
o Selected by Faculty of 1000
• Tay Y, Rinn J, Pandolfi PP. (2014) The multilayered complexity of ceRNA crosstalk and competition. Nature. 505, 344-352.

Candidates must have a proven track record in research and laboratory work in the form of publications in top English language journals. Ability to communicate in written and spoken English required. Applications should include full curriculum vitae, publication list, information on years of experience in research and laboratory work, and names and contact information (e-mail and telephone numbers) of three referees. Please also include a summary of your research experience, a brief description of the research you intend to focus on and why you are interested in the position applied.

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