Postdoctoral Position: Metabolic Regulation of Embryonic and Stem Cell Biology : Boston, MA, United States
A postdoctoral position is available in the developmental biology laboratory of Dr. Mary Loeken at the Joslin Diabetes Center, a teaching and research affiliate of Harvard Medical School. We study how altered glucose metabolism in embryos of diabetic mothers causes birth defects, especially neural tube defects, using mouse models, and neuronal precursors formed from embryonic and induced pluripotent stem cells. Current projects include metabolic pathways that regulate pluripotency and self-renewal, signaling pathways that regulate chromatin structure and gene expression during normal and diabetic conditions, and genetic variation in embryo/stem cell fuel metabolism.
Job Requirements
Applicants should be highly motivated, have a PhD or MD/PhD, and a strong background in molecular biology, stem cell biology, developmental biology, and biochemistry. Robust skills in ESC or iPSC culture; mouse handling; chromatin, RNA, and protein analyses; confocal/fluorescence microscopy; and molecular biology are preferred. Experience in Crispr/Cas9 technology would be an asset. Candidates must have a proven track record in laboratory research as demonstrated by publications in top English language journals. Ability to communicate in written and spoken English is required.
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