Ovarian Cancer Research - Post Doctoral Appointee
Post-doctoral position is available in the Department of Obstetrics and Gynecology, Indiana University School of Medicine for an OCRFA-funded project. The project focuses on the mutant p53-mediated signaling in high-grade serous ovarian cancer (HGSOC). About 96% of HGSOC harbor mutation in tumor suppressor gene, TP53. Our interests include: 1) role of ubiquitin proteasome system in mutant p53-mediated signaling; 2) epigenetic modifications in ovarian cancer with p53 mutations 3) establishing new mechanisms in tumor progression and metastasis; chemo-resistance and test the efficacy of small-molecule inhibitors in the ovarian cancer intervention.
Our research integrates in vitro organotypic 3D culture model of metastasis, mouse models, patient tumors, microarray, sequencing and proteomics-based approaches coupled with cell biology and molecular biology techniques. We consider highly motivated and creative candidates with a recently obtained Ph.D. degree and strong first-author publications.
Indiana University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, ethnicity, sex, gender identity, gender expression, genetic information, marital status, national origin, race, religion, sexual orientation, or veteran status.
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