招聘簡(jiǎn)介：

　　·南阿拉巴馬大學(xué)米切爾癌癥研究所

　　·地點(diǎn)：阿拉巴馬州，移動(dòng)

　　·工作編號(hào)：7056480

　　·發(fā)布日期：2019年3月14日

　　職位描述

　　美國(guó)南阿拉巴馬大學(xué)Mitchell癌癥研究所（美國(guó)-MCI）分子代謝腫瘤學(xué)項(xiàng)目主任Robert W.Sobol博士的實(shí)驗(yàn)室提供了一個(gè)校外資助的博士后職位。

　　這項(xiàng)任命將集中在頭頸部鱗狀細(xì)胞癌（HNSCC）的細(xì)胞和分子生物學(xué)。本項(xiàng)目將研究祖先信息標(biāo)記（AIMS）在選擇DNA修復(fù)和DNA損傷反應(yīng)基因中的作用，這可能有助于觀察到的患者在臨床結(jié)果方面的健康差異的生物學(xué)基礎(chǔ)。

　　英文原文：

　　·         University of South Alabama Mitchell Cancer Institute

　　·         Location: Mobile, AL

　　·         Job Number: 7056480

　　·         Posting Date: Mar 14, 2019

　　Job Description

　　An extramurally-funded postdoctoral position is available in the laboratory of Dr. Robert W. Sobol, Director of the Molecular & Metabolic Oncology program at the University of South Alabama Mitchell Cancer Institute (USA-MCI) in Mobile, AL, USA.

　　This appointment will focus on the cell and molecular biology of Head and Neck Squamous Cell Carcinoma (HNSCC). This project will investigate the role that Ancestry Informative Markers (AIMs) in select DNA repair and DNA damage response genes may contribute to the biological basis for the observed health disparity among patients with regard to clinical outcome.

　　This position will provide a unique opportunity to apply state-of-the-art cell biology, molecular biology and gene editing approaches to uncover mechanisms impacted by defects in select DNA repair and DNA damage response genes with an initial emphasis on DNA polymerase beta. The position requires a motivated postdoctoral fellow with experience in cell culture, flow cytometry, and molecular biology approaches. Experience with confocal microscopy techniques and gene editing would be a significant advantage as well.

　　The Mitchell Cancer Institute is a highly interactive and collaborative research environment where interdisciplinary research approaches are utilized to help improve our understanding of cancer, it’s treatment, and it’s prevention.

　　Qualifications

　　• PhD degree in cancer biology, biochemistry, toxicology, or pharmacology.

　　• The project also requires standard molecular biology techniques (PCR, cloning, immunoblotting), cell line cultivation and maintenance, standard toxicology techniques (cytotoxicity, comet, and ELISA or immunofluorescence).

　　• Experience with confocal microscopy is a plus.

　　• Excellent verbal and written communication skills in English.

　　Positions will be within the Department of Oncologic Sciences and the Mitchell Cancer Institute at the University of South Alabama. To apply, please send your curriculum vitae to: sobol.lab@gmail.com.

　　Applications will be reviewed and evaluated on an ongoing basis. The University of South Alabama is an Equal Opportunity Employer
Minorities/Females/Veterans/ Disabled.

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