招聘簡(jiǎn)介：
博士后在神經(jīng)退行性疾病研究中的地位
·凱西儲(chǔ)備大學(xué)
·地點(diǎn)：俄亥俄州克利夫蘭
·工作編號(hào)：7056496
·發(fā)布日期：2019年3月16日
職位描述
一個(gè)博士后職位立即可在凱斯西儲(chǔ)大學(xué)醫(yī)學(xué)院生理與生物物理學(xué)系的辛琦博士的實(shí)驗(yàn)室找到。
實(shí)驗(yàn)室主要研究線粒體病理學(xué)在神經(jīng)退行性疾病發(fā)病機(jī)制中的作用。我們結(jié)合體外細(xì)胞培養(yǎng)、體內(nèi)動(dòng)物模型和病人源性神經(jīng)元來(lái)研究神經(jīng)退行性變的機(jī)制。實(shí)驗(yàn)室的另一個(gè)研究重點(diǎn)是開(kāi)發(fā)治療人類(lèi)疾病的療法。我們一直在使用合理設(shè)計(jì)的蛋白質(zhì)-蛋白質(zhì)相互作用的肽抑制劑和高通量篩選來(lái)鑒定神經(jīng)疾病的治療方法。
英文原文：
A postdoc position on studying neurodegenerative diseases
· Case Western Reserve University
· Location: Cleveland, OH
· Job Number: 7056496
· Posting Date: Mar 16, 2019
Job Description
A postdoc position is immediately available in the laboratory of Dr. Xin Qi in the department of Physiology & Biophysics at Case Western Reserve University School of Medicine.
The lab focuses on mitochondrial pathology in the pathogenesis of neurodegenerative diseases. We use a combination of in vitro cell culture, in vivo animal models and patient-derived neurons to study the mechanisms of neurodegeneration. Another research focus of the lab is the development of therapeutics for the treatment of human diseases. We have been using the rationally designed peptide inhibitors of protein-protein interactions and high throughput screening to identify therapeutics for neurological disorders.
The successful applicant will participate in projects on elucidating molecular basis of our novel transgenic mouse models of neurodegenerative diseases. The qualified candidate will also be part of our drug discovery project for neurodegenerative diseases. The applicant must have a PhD and/or MD degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases and mouse models are highly desired.
Interested individuals should send a cover letter, CV, and the names/phone numbers of three people who could provide letters of reference by email to xxq38@case.edu.
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