招聘簡介：

　　博士后助理（白血病生物學和表觀遺傳學）

　　·邁阿密大學

　　·地點：佛羅里達州邁阿密

　　·工作編號：7056858（參考號：R100028319）

　　·發(fā)布日期：2019年4月9日

　　·申請截止日期：開放至填寫

　　職位描述

　　邁阿密大學醫(yī)療系統(tǒng)和米勒醫(yī)學院的西爾維斯特綜合癌癥中心為博士后助理提供了一個激動人心的機會。該職位的重點將是癌癥表觀遺傳學項目，并將在高度協(xié)作的環(huán)境中研究白血病表觀遺傳調控和正常造血的分子機制。

　　我們目前正在尋找一位積極性很高的博士后，具有深入的細胞和分子生物學知識和廣泛的技能，以加入實驗室。候選人應在各種實驗室技術，包括細胞培養(yǎng)和分子生物學分析（分子克隆，細胞增殖分析，亞群體分析）的專業(yè)知識。通過facs分析、穩(wěn)定和短暫的轉染、shRNA和病毒結構的使用、DNA和RNA的制備和分析（質粒的制備、常規(guī)pcr和rt-pcr）、染色質免疫沉淀（chip）分析、生化分析（elisa、免疫印跡、co-ip）。項目將包括體內和體外候選基因建模，以確定有助于造血惡性腫瘤發(fā)展的表觀遺傳沉默基因，并利用體內和體外系統(tǒng)對候選基因進行表征。

　　英文原文：

　　Postdoctoral Associate (Leukemia Biology and Epigenetics)

　　·         University of Miami

　　·         Location: Miami, FL

　　·         Job Number: 7056858 (Ref #: R100028319)

　　·         Posting Date: Apr 9, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　The Sylvester Comprehensive Cancer Center with the University of Miami Health System and Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate. The focus of this position will be in the Cancer Epigenetics Program and will work in a highly collaborative environment investigating the molecular mechanisms of epigenetic regulation of leukemia and normal hematopoiesis.

　　We are currently seeking a highly motivated Postdoctoral Associate with in-depth knowledge and extensive skills in cellular and molecular biology to join the lab. The candidates should demonstrate expertise in various lab techniques including cell culture and molecular biology assays (molecular cloning, cell proliferation assay, subpopulation analysis by FACS, stable and transient transfection, use of shRNA and viral constructs), preparation and analysis of DNA and RNA (preparation of plasmids, regular PCR and RT-PCR), chromatin immunoprecipitation (ChIP) assays, biochemical assays (ELISA, immunoblotting, Co-IP). Projects will include in vivo and in vitro modeling of candidate genes to identify epigenetically silenced genes that contribute to the development of hematopoietic malignancies and characterization of candidate genes using in vitro and in vivo systems.

　　Minimum Qualifications

　　Ph.D. or other doctoral-level degree in a relevant field of study, or M.D. Strong molecular biology or cancer biology skills. Previous experience with epigenetics, cancer modeling or hematopoiesis is preferred. Evidence of scholarly ability (record of publication in peer-reviewed journals, etc.) must be presented. Ability to communicate in written and spoken English is required. It is expected that the candidate will have the ability to work independently, design experiments with appropriate controls, collect and tabulate data, publish and present results, as well as to participate in the training of graduate and rotation students in a research laboratory setting.

　　UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

　　Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University of Miami School of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.

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