美國(guó)希望之城2025年招聘博士后職位（白血病和癌癥的藥物開(kāi)發(fā)）

希望之城國(guó)家醫(yī)療中心(City of Hope NationalMedical Center)是一所頂尖的美國(guó)非盈利研究和治療中心，專注于癌癥、糖尿病和其他危及生命的疾病。

Postdoctoral Fellow - Drug Development for Leukemia and Cancer

City of Hope

Job Description

Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratory of Dr. Le Xuan Truong Nguyen in the Department of Hematological Malignancies and Translational Sciences is seeking highly motivated and innovative Postdoctoral Fellow. This is an excellent opportunity to join a well-established team and lead projects that culminate in publications in high-impact journals.

Our research focuses on drug development, uncovering basic mechanisms, and identifying novel therapeutic targets in leukemogenesis and solid tumors. Specifically, we study genetic and epigenetic biomarkers with prognostic value in acute myeloid leukemia (AML) and other solid cancers. Our work emphasizes therapeutic candidates targeting mitochondrial vulnerabilities, including nucleoside analogs, small GTPase inhibitors, natural plant extracts, and immunotherapies.

As a successful candidate you will:

· Lead projects by designing and performing experimental procedures

· Manage data, analyze, and report findings

· Write scientific papers and grants

· Work with PI and other team members to perform experiments in vitro and in vivo

· Utilize the following in vitro skills (not limited to but including):

o Aseptic techniques, cell culture, western blot, RNA/DNA extraction, protein extraction, RT-qPCR, seahorse, northern blot, bacterial transformation, cloning, lentivirus production, etc.

· Utilize the following in vivo skills (not limited to but including):

o Basic routes of administration (oral gavage, intraperitoneal, retro-orbital, subcutaneous, intra-venous injections), blood collection, organ harvesting (spleen, bone marrow, liver, etc.)

· Ph.D. or M.D. in a relevant field.

· Preferred experience in molecular signaling, cancer biology, leukemia research, and extensive murine studies.

· Experience in immunology is an advantage.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here

Salary / Pay Rate Information:

Pay Rate: $34.00 - $37.55 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

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